Cheesy Holiday Chicken Biscuit Casserole is the ultimate comfort food for the festive season. Creamy, rich, and filled with tender chicken, fluffy biscuit pieces, and plenty of melted cheese, this casserole is everything you want in a cozy holiday dinner. It’s warm, satisfying, and perfect for feeding a crowd with minimal effort.
This dish combines classic comfort flavors with holiday ease. Using simple ingredients and a one-pan baking method, this casserole comes together quickly and delivers big flavor. Whether you’re serving it for a Christmas Eve dinner, a casual holiday gathering, or a cozy family night, Cheesy Holiday Chicken Biscuit Casserole is guaranteed to be a hit.
Why You’ll Love This Cheesy Holiday Chicken Biscuit Casserole
- Creamy, cheesy, and incredibly comforting
- Made with tender chicken and fluffy biscuits
- Easy one-dish meal with minimal cleanup
- Perfect for holidays, potlucks, and family dinners
- Customizable with vegetables or different cheeses
- Kid-friendly and crowd-pleasing
Why You Should Try This Recipe
This recipe is ideal when you want something warm and satisfying without spending hours in the kitchen. It uses convenient ingredients, bakes beautifully in one dish, and reheats well. The combination of biscuits and creamy chicken makes it feel indulgent while still being easy enough for busy holiday schedules.
Ingredients You’ll Need
- 2 cups cooked chicken, shredded or diced (rotisserie works great)
- 1 can refrigerated biscuit dough, cut into quarters
- 1 can cream of chicken soup
- ½ cup sour cream
- 1 cup milk
- 1 ½ cups shredded cheddar cheese
- ½ cup shredded mozzarella cheese
- 1 teaspoon garlic powder
- ½ teaspoon onion powder
- ½ teaspoon black pepper
- Salt, to taste
- 1 cup frozen mixed vegetables (optional: peas, carrots, corn)
- Fresh parsley or thyme for garnish (optional)
How to Make Cheesy Holiday Chicken Biscuit Casserole
Step 1 — Preheat and Prepare
Preheat oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish.
Step 2 — Make the Creamy Base
In a large bowl, whisk together cream of chicken soup, sour cream, milk, garlic powder, onion powder, salt, and pepper until smooth.
Step 3 — Add Chicken and Biscuits
Stir in the cooked chicken and biscuit pieces. If using vegetables, fold them in now.
Step 4 — Add Cheese
Mix in 1 cup of the shredded cheddar cheese. Pour the mixture evenly into the prepared baking dish.
Step 5 — Top and Bake
Sprinkle the remaining cheddar and mozzarella over the top. Bake uncovered for 35–40 minutes, or until biscuits are cooked through and the top is golden and bubbly.
Step 6 — Rest and Serve
Let the casserole rest for 5 minutes before serving. Garnish with fresh herbs if desired.
Nutritional Information (Approx. per serving)
- Calories: 480
- Fat: 26g
- Carbohydrates: 36g
- Protein: 24g
- Fiber: 2g
Values may vary depending on ingredients used.
Tips for the Best Cheesy Holiday Chicken Biscuit Casserole
- Cut biscuits into even pieces so they bake evenly
- Use cooked chicken to save time
- Stir the mixture well so biscuits are fully coated
- Cover loosely with foil if the top browns too quickly
- Let the casserole rest before serving to set properly
Variations & Substitutions
- Use cream of mushroom soup instead of chicken
- Swap cheddar for Colby Jack or Monterey Jack
- Add sautéed onions or mushrooms for more depth
- Use Greek yogurt instead of sour cream
- Make it spicy with a pinch of cayenne or diced jalapeños
What to Serve with Cheesy Holiday Chicken Biscuit Casserole
- Simple green salad
- Steamed green beans or broccoli
- Roasted vegetables
- Cranberry sauce for a holiday touch
- Warm dinner rolls
Common Mistakes to Avoid
- Using raw chicken (must be cooked first)
- Overcrowding the biscuits so they don’t cook through
- Skipping seasoning—the sauce needs flavor
- Serving immediately without resting
Storing Tips for the Recipe
- Store leftovers in an airtight container for up to 4 days
- Reheat in the oven or microwave with a splash of milk
- Not recommended for freezing due to biscuit texture
- Best enjoyed fresh or within a few days
Conclusion
Cheesy Holiday Chicken Biscuit Casserole is a warm, comforting dish that belongs on your holiday table. With its creamy sauce, tender chicken, fluffy biscuits, and melted cheese, it’s the kind of meal that brings everyone back for seconds. Easy to make and deeply satisfying, this casserole is perfect for Christmas gatherings or cozy winter dinners.
General Information
- Course: Main Dish / Casserole
- Prep Time: 15 minutes
- Cook Time: 40 minutes
- Total Time: 55 minutes
- Servings: 6
- Difficulty: Easy
Frequently Asked Questions (FAQ)
Can I make this ahead of time?
Yes. Assemble the casserole, cover, and refrigerate for up to 24 hours. Bake when ready.
Can I use canned chicken?
Yes, but freshly cooked or rotisserie chicken has better texture and flavor.
How do I know the biscuits are cooked?
They should be fluffy and no longer doughy in the center.
Can I make it lighter?
Use low-fat cheese, milk, and Greek yogurt instead of sour cream.
Can I add vegetables?
Absolutely. Frozen peas, carrots, corn, or green beans work well.